Of mice and CRISPR: The post-CRISPR future of the mouse as a model system for the human condition

EMBO Rep. 2017 Feb;18(2):187-193. doi: 10.15252/embr.201643717. Epub 2017 Jan 24.


The mouse has been a major model system for biomedical research. Gene editing technologies will further increase its importance for studying the human condition and human diseases.

MeSH terms

  • Animals
  • CRISPR-Cas Systems*
  • Disease Models, Animal*
  • Genetic Engineering / methods
  • Genetic Engineering / trends*
  • Humans
  • Mice / genetics*