An overview of osteoporosis and frailty in the elderly

BMC Musculoskelet Disord. 2017 Jan 26;18(1):46. doi: 10.1186/s12891-017-1403-x.


Osteoporosis and osteoporotic fractures remain significant public health challenges worldwide. Recently the concept of frailty in relation to osteoporosis in the elderly has been increasingly accepted, with emerging studies measuring frailty as a predictor of osteoporotic fractures. In this overview, we reviewed the relationship between frailty and osteoporosis, described the approaches to measuring the grades of frailty, and presented current studies and future research directions investigating osteoporosis and frailty in the elderly. It is concluded that measuring the grades of frailty in the elderly could assist in the assessment, management and decision-making for osteoporosis and osteoporotic fractures at a clinical research level and at a health care policy level.

Keywords: Ageing; Frailty; Geriatrics; Osteoporosis; Osteoporotic fractures.

Publication types

  • Review

MeSH terms

  • Accidental Falls
  • Aged
  • Aged, 80 and over
  • Biomedical Research / methods
  • Biomedical Research / trends*
  • Clinical Decision-Making
  • Frail Elderly
  • Frailty / diagnosis
  • Frailty / etiology*
  • Humans
  • Osteoporosis / complications*
  • Osteoporotic Fractures / etiology*
  • Risk Assessment
  • Risk Factors