The cost of seeking an edge: Recurrent renal infarction in setting of recreational use of anabolic steroids

Ann Med Surg (Lond). 2017 Jan 12:14:25-28. doi: 10.1016/j.amsu.2017.01.015. eCollection 2017 Feb.

Abstract

Introduction: Anabolic-androgenic steroid (AAS) use and testosterone therapy have been well established risk factors for the creation of a pro-thrombotic state, and to precipitate formation of thromboemboli in individuals already predisposed to thrombosis.

Case report: Here, we present the case of an amateur bodybuilder, with a negative thrombophilia workup, who experienced primary renal infarction while using the AAS trenbolone acetate and testosterone, as well as a subsequent renal infarction while anticoagulated with apixaban.

Discussion: The development of subsequent infarctions in an anticoagulated patient with discontinued recreational steroid use poses a unique situation and challenges the current understanding of a thrombophilic state associated with steroids. The lifetime prevalence of anabolic steroid use is estimated to be 1% in the male population in the United States which is significant.

Conclusion: Further understanding and recommendations of appropriate anticoagulant should be further elucidated to appropriately medically manage patients from this confounding social and medical history.

Keywords: Anabolic; Renal artery thrombus; Renal infarction; Steroids.

Publication types

  • Case Reports