PET+MR versus PET/CT in the initial staging of head and neck cancer, using a trimodality PET/CT+MR system

Clin Imaging. 2017 Mar-Apr;42:232-239. doi: 10.1016/j.clinimag.2017.01.003. Epub 2017 Jan 17.

Abstract

Purpose: To compare the diagnostic accuracy of PET+MR with PET/CT in the initial staging of head and neck cancer.

Materials and methods: Contrast-enhanced PET/CT+MR was performed in 27 patients with newly diagnosed head and neck cancer. PET/CT and PET+MR were evaluated separately, and the TNM stage and factors influencing treatment were assessed.

Results: The TNM staging by PET+MR was comparable to PET/CT (T: p=0.331, N: p=0.453, M: p=0.034). The sensitivity/specificity/accuracy of treatment-influencing factors by PET/CT and PET+MR were 0.68/0.99/0.97, and 1.00/1.00/0.99, respectively.

Conclusions: Whole-body staging with PET+MR yields at least equal diagnostic accuracy as PET/CT in head and neck cancer.

Keywords: ENT surgery; Head and neck cancer; Oncology; PET/CT; PET/MR.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Fluorodeoxyglucose F18
  • Head and Neck Neoplasms / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Multimodal Imaging
  • Neoplasm Staging
  • Positron Emission Tomography Computed Tomography*
  • Positron-Emission Tomography*
  • Prospective Studies
  • Radiopharmaceuticals
  • Sensitivity and Specificity

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18