Rapid, sensitive, and reusable detection of glucose by highly monodisperse nickel nanoparticles decorated functionalized multi-walled carbon nanotubes

Biosens Bioelectron. 2017 May 15:91:728-733. doi: 10.1016/j.bios.2017.01.045. Epub 2017 Jan 22.

Abstract

Addressed herein, functionalized multi-walled carbon nanotube (MWCNT) supported highly monodisperse nickel nanoparticles modified on glassy carbon electrode (Ni@f-MWCNT/GCE) were synthesized through microwave assisted method and examined for non-enzymatic glucose sensing in ionic liquids by cyclic voltammetry and chronoamperometry. The results of Ni@f-MWCNT/GCE electrode were compared with Ni NPs/GCE electrode and the results revealed that f-MWCNTs increased the electrocatalytic properties of Ni nanoparticles regarding glucose oxidation. They also demonstrated a good linear span of 0.05-12.0mM and a detection boundary of 0.021µM. Specifically, in the amperometric signal of the electrodes after 200th cycles, no major change was observed. This non-enzymatic glucose sensor presents one of the record electrocatalytic activity, stability and response towards glucose under the optimized situations. As a result, prepared novel Ni@f-MWCNT/GCE was utilized to detect glucose in real serum species.

Keywords: Glucose detection; Microwave; Nanosensor; Ni@f-MWCNT.

Publication types

  • Evaluation Study

MeSH terms

  • Biosensing Techniques / economics
  • Biosensing Techniques / methods
  • Blood Glucose / analysis*
  • Electrochemical Techniques / economics
  • Electrochemical Techniques / methods*
  • Electrodes
  • Humans
  • Limit of Detection
  • Metal Nanoparticles / chemistry*
  • Metal Nanoparticles / ultrastructure
  • Nanotubes, Carbon / chemistry*
  • Nanotubes, Carbon / ultrastructure
  • Nickel / chemistry*
  • Oxidation-Reduction
  • Time Factors

Substances

  • Blood Glucose
  • Nanotubes, Carbon
  • Nickel