TRAPPing Rab18 in lipid droplets

EMBO J. 2017 Feb 15;36(4):394-396. doi: 10.15252/embj.201696287. Epub 2017 Jan 27.

Abstract

A number of membrane trafficking components are associated with lipid droplets (LDs) and/or are involved in their biogenesis. In this issue of The EMBO Journal, Li et al (2017) show that the mammalian TRAPPII (TRAnsport Protein Particle) complex acts as an LD‐associated GEF for Rab18, thereby regulating LD homeostasis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Lipid Droplets*
  • Lipid Metabolism
  • rab GTP-Binding Proteins*

Substances

  • rab GTP-Binding Proteins