Penile transplantation: an emerging option for genitourinary reconstruction

Transpl Int. 2017 May;30(5):441-450. doi: 10.1111/tri.12928. Epub 2017 Mar 5.

Abstract

Penile transplantation is an emerging option for patients with severe genital defects not amenable to traditional reconstructive options. In this article, we discuss the burgeoning problem of severe male genitourinary trauma in the military, the limitations of traditional reconstructive options in addressing these problems, and the potential for penile transplantation to provide improved outcomes. We also review the preclinical research and limited worldwide experience with penile transplantation to date, including lessons learned, and discuss the many important technical, logistical, and ethical considerations pertaining to penile transplantation that must be addressed to maximize the likelihood of successful implementation.

Keywords: penile defects; penile transplant; reconstructive surgical procedures; vascularized composite allotransplantation.

Publication types

  • Review

MeSH terms

  • Humans
  • Male
  • Penile Transplantation*
  • Penis / physiology
  • War-Related Injuries / surgery