Geriatric Syncope and Cardiovascular Risk in the Emergency Department

J Emerg Med. 2017 Apr;52(4):438-448.e3. doi: 10.1016/j.jemermed.2016.12.003. Epub 2017 Jan 26.

Abstract

Background: Syncope is a transient loss of consciousness that is caused by a brief loss in generalized cerebral blood flow.

Objective: This article reviews the background, epidemiology, etiologies, evaluation, and disposition considerations of geriatric patients with syncope, with a focus on cardiovascular risk.

Discussion: Although syncope is one of the most common symptoms in elderly patients presenting to the emergency department, syncope causes in geriatric patients can present differently than in younger populations, and the underlying etiology is often challenging to discern. History, physical examination, and electrocardiography (ECG) have the greatest utility in evaluating syncope. Additional testing should be guided by history and physical examination. There are multiple scoring tools developed to aid in management and these are reviewed in the article. Common predictors that would indicate a need for further work-up include a history of cardiac or valvular disease (i.e., ventricular dysrhythmia, congestive heart failure), abnormal ECG, anemia or severe volume depletion (i.e., from a gastrointestinal bleed), syncope while supine or with effort, report of palpitations or chest pain, persistent abnormal vital signs, or family history of sudden death. With advancing age, cardiovascular morbidity plays a more frequent and important role in the etiology of syncope.

Conclusions: The syncope work-up should be tailored to the patient's presentation. Disposition should be based on the results of the initial evaluation and risk factors for adverse outcomes.

Keywords: cardiovascular risk; emergency medicine; geriatrics; presyncope; syncope.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antihypertensive Agents / adverse effects
  • Antihypertensive Agents / pharmacokinetics
  • Arrhythmias, Cardiac / complications
  • Cardiovascular Diseases / complications*
  • Cardiovascular Diseases / physiopathology
  • Consciousness Disorders / etiology
  • Diagnosis, Differential
  • Drug-Related Side Effects and Adverse Reactions / complications*
  • Emergency Service, Hospital / organization & administration
  • Female
  • Geriatrics / methods
  • Health Status Indicators*
  • Humans
  • Male
  • Psychotropic Drugs / adverse effects
  • Psychotropic Drugs / pharmacokinetics
  • Syncope / etiology*
  • Vasodilator Agents / adverse effects
  • Vasodilator Agents / pharmacokinetics

Substances

  • Antihypertensive Agents
  • Psychotropic Drugs
  • Vasodilator Agents