Purple Sweet Potato Attenuate Weight Gain in High Fat Diet Induced Obese Mice

J Food Sci. 2017 Mar;82(3):787-793. doi: 10.1111/1750-3841.13617. Epub 2017 Jan 30.


Purple sweet potato (PSP) is widely grown in Asia and considered as a healthy vegetable. The objective of the current study was to determine the anti-obesity effect of the PSP on high fat diet induced obese C57BL/6J mice. The mice were administrated with high fat diet supplemented with the sweet potato (SP) or PSP at the concentration of 15% and 30% for 12 wk, respectively. The results showed that the supplementation of SP or PSP at 30% significantly ameliorated high fat diet induced obesity and its associated risk factors, including reduction of body weight and fat accumulation, improvement of lipid profile and modulation of energy expenditure. Moreover, PSP also posed beneficial effect on the liver and kidney functions. These results indicate that PSP and SP have anti-obesity effect and are effective to reduce the metabolic risk.

Keywords: energy expenditure; lipid profile; obesity; purple sweet potato; sweet potato.

MeSH terms

  • Adipose Tissue / metabolism
  • Animals
  • Anthocyanins / pharmacology
  • Anthocyanins / therapeutic use
  • Asia
  • Body Weight / drug effects
  • Diet, High-Fat / adverse effects*
  • Dietary Fiber / pharmacology
  • Dietary Fiber / therapeutic use
  • Energy Metabolism / drug effects
  • Ipomoea batatas / chemistry*
  • Kidney / drug effects
  • Kidney / metabolism
  • Lipids / blood
  • Liver / drug effects
  • Liver / metabolism
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Obese
  • Obesity / blood
  • Obesity / diet therapy*
  • Obesity / metabolism
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plant Tubers*
  • Weight Gain*


  • Anthocyanins
  • Dietary Fiber
  • Lipids
  • Plant Extracts