Evolving health care through personal genomics

Nat Rev Genet. 2017 Apr;18(4):259-267. doi: 10.1038/nrg.2016.162. Epub 2017 Jan 31.


With the rapid evolution of next-generation DNA sequencing technologies, the cost of sequencing a human genome has plummeted, and genomics has started to pervade health care across all stages of life - from preconception to adult medicine. Challenges to fully embracing genomics in a clinical setting remain, but some approaches are starting to overcome these barriers, such as community-driven data sharing to improve the accuracy and efficiency of applying genomics to patient care.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Delivery of Health Care / standards*
  • Genetic Testing / methods*
  • Genome, Human
  • Genomics / methods*
  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Precision Medicine*