Joint Loading in Runners Does Not Initiate Knee Osteoarthritis

Exerc Sport Sci Rev. 2017 Apr;45(2):87-95. doi: 10.1249/JES.0000000000000105.


Runners do not have a greater prevalence of knee osteoarthritis (OA) than nonrunners. The hypothesis that joint loads in running do not cause OA is forwarded. Two mechanisms are proposed: 1) cumulative load, which is surprisingly low in running, is more important for OA risk than peak load, and 2) running conditions cartilage to withstand the mechanical stresses of running.

Publication types

  • Review

MeSH terms

  • Biomechanical Phenomena
  • Cartilage, Articular / physiology*
  • Humans
  • Knee Joint / physiology*
  • Osteoarthritis, Knee / physiopathology*
  • Pain / physiopathology
  • Risk Factors
  • Running / physiology*
  • Stress, Mechanical
  • Weight-Bearing / physiology