Case Report: Severe hypernatremia from psychogenic adipsia

F1000Res. 2017 Jan 11;6:34. doi: 10.12688/f1000research.9181.1. eCollection 2017.


Hypernatremia is a common emergency room presentation and carries high mortality. We describe a case of a 56-year-old male patient with who presents with refusal to drink water for several weeks leading to the admission. He was diagnosed with psychogenic adipsia and was treated successfully with fluids, mirtazapine and clonazepam.

Keywords: adipsia; altered mental status; hypernatremia; infection; osmolality; osmotic demyelination; paranoia; stroke.

Grant support

The author(s) declared that no grants were involved in supporting this work.