Study of efficacy of esthetic High-Intensity Focused Ultrasound system on Iranian skin for reducing the laxity and wrinkles of aging

J Cosmet Dermatol. 2017 Sep;16(3):336-341. doi: 10.1111/jocd.12317. Epub 2017 Feb 2.


Background: Ultrasound is a mechanical wave that transmitted in a straight line and it can be focused at frequencies of 1-7 MHz with a high degree of precision. An important aspect of HIFU is that damaging focal point is located several millimeters below the surface of the skin and tissue above and below the focal point remains unaffected. Due to absorption of this energy, temperature of tissue rises to more than 60°C and this stimulates the cells for collagen production and tissue rejuvenation.

Objective: To evaluate the clinical efficacy and safety of High-Intensity Focused Ultrasound on Skin Laxity and wrinkles.

Material and method: The study involved 22 women aged 35-62 with skin type II-IV. HIFU device with three transducers was employed. Various focal depths with different energies were used in accordance with skin thickness. Improvement for seven regions of face and whole face were evaluated by two dermatologists and patients 3 months after treatment.

Results: All of the patients completed the study. Three months after treatment, there was a highly statistical improvement in skin laxity for all of the patients. Also, the average percentage of improvement by doctor's opinion and patients was 58% and 60%, respectively.

Conclusion: The experimental data obtained from dermatologists and patients showed that HIFU appears to be a safe and effective modality for skin laxity treatment.

Keywords: HIFU; Ultrasound; anti-aging; facial rejuvenation; skin laxity.

MeSH terms

  • Adult
  • Cosmetic Techniques* / adverse effects
  • Edema / etiology
  • Erythema / etiology
  • Esthetics
  • Face*
  • Female
  • Humans
  • Iran
  • Middle Aged
  • Pain / etiology
  • Patient Satisfaction
  • Rejuvenation
  • Skin Aging*
  • Treatment Outcome
  • Ultrasonic Therapy / adverse effects
  • Ultrasonic Therapy / methods*