Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay

doi:10.1128/JCM.02471-16

. 2017 Apr;55(4):1223-1225.

doi: 10.1128/JCM.02471-16. Epub 2017 Feb 1.

Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay

David W Wareham^{1

2}, Muhd Haziq F Abdul Momin³

Affiliations

¹ Antimicrobial Research Group, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom d.w.wareham@qmul.ac.uk.
² Division of Infection, Barts Health NHS Trust, London, United Kingdom.
³ Antimicrobial Research Group, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

PMID: 28151407
PMCID: PMC5377851
DOI: 10.1128/JCM.02471-16

Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay

David W Wareham et al. J Clin Microbiol. 2017 Apr.

. 2017 Apr;55(4):1223-1225.

doi: 10.1128/JCM.02471-16. Epub 2017 Feb 1.

Authors

David W Wareham^{1

2}, Muhd Haziq F Abdul Momin³

Affiliations

¹ Antimicrobial Research Group, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom d.w.wareham@qmul.ac.uk.
² Division of Infection, Barts Health NHS Trust, London, United Kingdom.
³ Antimicrobial Research Group, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.

PMID: 28151407
PMCID: PMC5377851
DOI: 10.1128/JCM.02471-16

No abstract available

Keywords: KPC; NDM; OXA-48; carbapenems; rapid diagnostics.

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Figures

**FIG 1**
Detection of OXA-48, KPC, and NDM-like carbapenemases in isolates producing single and dual enzymes using the Resist-3 O.K.N. assay. NEG, negative; POS, positive.

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References

1. Otter JA, Burgess P, Davies F, Mookerjee S, Singleton J, Gilchrist M, Parsons D, Brannigan ET, Robotham J, Holmes AH. 13 October 2016. Counting the cost of an outbreak of carbapenemase-producing Enterobacteriaceae: an economic evaluation from a hospital perspective. Clin Microbiol Infect doi:10.1016/j.cmi.2016.10.005. - DOI - PubMed
1. Lutgring JD, Limbago BM. 2016. The problem of carbapenemase-producing-carbapenem-resistant-Enterobacteriaceae detection. J Clin Microbiol 54:529–534. doi:10.1128/JCM.02771-15. - DOI - PMC - PubMed
1. Wareham DW, Shah R, Betts JW, Phee LM, Momin MH. 2016. Evaluation of an immunochromatographic lateral flow assay (OXA-48 K-SeT) for rapid detection of OXA-48-like carbapenemases in Enterobacteriaceae. J Clin Microbiol 54:471–473. doi:10.1128/JCM.02900-15. - DOI - PMC - PubMed
1. Glupczynski Y, Evrard S, Ote I, et al. . 2016. Evaluation of two new commercial immunochromatographic assays for the rapid detection of OXA-48 and KPC carbapenemases from cultured bacteria. J Antimicrob Chemother 71:1217–1222. doi:10.1093/jac/dkv472. - DOI - PubMed
1. Dortet L, Jousset A, Sainte-Rose V, Cuzon G, Naas T. 2016. Prospective evaluation of the OXA-48 K-SeT assay, an immunochromatographic test for the rapid detection of OXA-48-type carbapenemases. J Antimicrob Chemother 71:1834–1840. doi:10.1093/jac/dkw058. - DOI - PubMed

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[1] Otter JA, Burgess P, Davies F, Mookerjee S, Singleton J, Gilchrist M, Parsons D, Brannigan ET, Robotham J, Holmes AH. 13 October 2016. Counting the cost of an outbreak of carbapenemase-producing Enterobacteriaceae: an economic evaluation from a hospital perspective. Clin Microbiol Infect doi:10.1016/j.cmi.2016.10.005. - DOI - PubMed

[2] Otter JA, Burgess P, Davies F, Mookerjee S, Singleton J, Gilchrist M, Parsons D, Brannigan ET, Robotham J, Holmes AH. 13 October 2016. Counting the cost of an outbreak of carbapenemase-producing Enterobacteriaceae: an economic evaluation from a hospital perspective. Clin Microbiol Infect doi:10.1016/j.cmi.2016.10.005. - DOI - PubMed

[3] Lutgring JD, Limbago BM. 2016. The problem of carbapenemase-producing-carbapenem-resistant-Enterobacteriaceae detection. J Clin Microbiol 54:529–534. doi:10.1128/JCM.02771-15. - DOI - PMC - PubMed

[4] Lutgring JD, Limbago BM. 2016. The problem of carbapenemase-producing-carbapenem-resistant-Enterobacteriaceae detection. J Clin Microbiol 54:529–534. doi:10.1128/JCM.02771-15. - DOI - PMC - PubMed

[5] Wareham DW, Shah R, Betts JW, Phee LM, Momin MH. 2016. Evaluation of an immunochromatographic lateral flow assay (OXA-48 K-SeT) for rapid detection of OXA-48-like carbapenemases in Enterobacteriaceae. J Clin Microbiol 54:471–473. doi:10.1128/JCM.02900-15. - DOI - PMC - PubMed

[6] Wareham DW, Shah R, Betts JW, Phee LM, Momin MH. 2016. Evaluation of an immunochromatographic lateral flow assay (OXA-48 K-SeT) for rapid detection of OXA-48-like carbapenemases in Enterobacteriaceae. J Clin Microbiol 54:471–473. doi:10.1128/JCM.02900-15. - DOI - PMC - PubMed

[7] Glupczynski Y, Evrard S, Ote I, et al. . 2016. Evaluation of two new commercial immunochromatographic assays for the rapid detection of OXA-48 and KPC carbapenemases from cultured bacteria. J Antimicrob Chemother 71:1217–1222. doi:10.1093/jac/dkv472. - DOI - PubMed

[8] Glupczynski Y, Evrard S, Ote I, et al. . 2016. Evaluation of two new commercial immunochromatographic assays for the rapid detection of OXA-48 and KPC carbapenemases from cultured bacteria. J Antimicrob Chemother 71:1217–1222. doi:10.1093/jac/dkv472. - DOI - PubMed

[9] Dortet L, Jousset A, Sainte-Rose V, Cuzon G, Naas T. 2016. Prospective evaluation of the OXA-48 K-SeT assay, an immunochromatographic test for the rapid detection of OXA-48-type carbapenemases. J Antimicrob Chemother 71:1834–1840. doi:10.1093/jac/dkw058. - DOI - PubMed

[10] Dortet L, Jousset A, Sainte-Rose V, Cuzon G, Naas T. 2016. Prospective evaluation of the OXA-48 K-SeT assay, an immunochromatographic test for the rapid detection of OXA-48-type carbapenemases. J Antimicrob Chemother 71:1834–1840. doi:10.1093/jac/dkw058. - DOI - PubMed

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Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay

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Rapid Detection of Carbapenemases in Enterobacteriaceae: Evaluation of the Resist-3 O.K.N. (OXA-48, KPC, NDM) Lateral Flow Multiplexed Assay

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