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. 2017 Sep;19(9):847-853.
doi: 10.1080/10286020.2016.1271793. Epub 2017 Feb 2.

Three new triterpenoids from Ganoderma theaecolum

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Three new triterpenoids from Ganoderma theaecolum

Li-Ying Liu et al. J Asian Nat Prod Res. 2017 Sep.

Abstract

Three new triterpenoids (1-3), together with four known triterpenoids (4-7), were isolated from the fruiting bodies of Ganoderma theaecolum. Their structures were elucidated on the basis of their spectroscopic data and chemical evidence. Compounds 4 and 6 exhibited antitumor activities against H460 cells with IC50 values of 22.4 and 43.1 μM, respectively. And the cytotoxic activities of compounds 4 and 5 against MDA-MB-231 cancer cell lines were assayed with IC50 values of 49.1 and 75.8 μM, respectively.

Keywords: Ganoderma; Ganoderma theaecolum; Ganodermataceae; antitumor activities; triterpenoids.

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