Odontogenic Cysts and Neoplasms

Surg Pathol Clin. 2017 Mar;10(1):177-222. doi: 10.1016/j.path.2016.10.006. Epub 2016 Dec 29.


This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and diagnostic pitfalls are addressed for inflammatory cysts (periapical cyst, mandibular infected buccal cyst/paradental cyst), developmental cysts (dentigerous, lateral periodontal, glandular odontogenic, orthokeratinized odontogenic cyst), benign tumors (keratocystic odontogenic tumor, ameloblastoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma and fibroodontoma, odontoma, squamous odontogenic tumor, calcifying cystic odontogenic tumor, primordial odontogenic tumor, central odontogenic fibroma, and odontogenic myxomas), and malignant tumors (clear cell odontogenic carcinoma, ameloblastic carcinoma, ameloblastic fibrosarcoma).

Keywords: Ameloblastoma; Calcifying epithelial odontogenic tumor; Clear cell odontogenic carcinoma; Gnathic; Keratocystic odontogenic tumor; Odontogenic cysts; Odontoma.

Publication types

  • Review

MeSH terms

  • Dentigerous Cyst / diagnosis
  • Dentigerous Cyst / pathology
  • Diagnosis, Differential
  • Humans
  • Odontogenic Cysts / diagnosis*
  • Odontogenic Cysts / pathology
  • Odontogenic Tumors / diagnosis*
  • Odontogenic Tumors / pathology
  • Periodontal Cyst / diagnosis
  • Periodontal Cyst / pathology
  • Prognosis
  • Radicular Cyst / diagnosis
  • Radicular Cyst / pathology
  • Radiography, Dental