Kounis syndrome: A review article on epidemiology, diagnostic findings, management and complications of allergic acute coronary syndrome

Mahmoud Abdelghany; Rogin Subedi; Siddharth Shah; Hani Kozman

doi:10.1016/j.ijcard.2017.01.124

Kounis syndrome: A review article on epidemiology, diagnostic findings, management and complications of allergic acute coronary syndrome

Int J Cardiol. 2017 Apr 1:232:1-4. doi: 10.1016/j.ijcard.2017.01.124. Epub 2017 Jan 27.

Authors

Mahmoud Abdelghany¹, Rogin Subedi², Siddharth Shah², Hani Kozman²

Affiliations

¹ Department of Medicine, Division of Cardiology, State University of New York, Upstate Medical University, Syracuse, NY, USA. Electronic address: abdelghm@upstate.edu.
² Department of Medicine, Division of Cardiology, State University of New York, Upstate Medical University, Syracuse, NY, USA.

PMID: 28153536
DOI: 10.1016/j.ijcard.2017.01.124

Abstract

Kounis syndrome (KS) is a hypersensitivity coronary disorder induced by exposure to drugs, food, environmental and other triggers. Vasospastic allergic angina, allergic myocardial infarction (MI) and stent thrombosis with occluding thrombus infiltrated by eosinophils and/or mast cells constitute the three main variants of this syndrome. We reviewed 175 patients who fulfilled the definition of one of the three types of KS. The epidemiology, diagnostic findings, management and complications were reviewed in this article.

Keywords: Allergic acute coronary syndrome; Coronary vasospasm; Kounis syndrome; Myocardial infarction; Stent thrombosis.

Publication types

Review

MeSH terms

Anti-Allergic Agents / therapeutic use*
Coronary Angiography
Diagnostic Imaging / methods*
Disease Management
Echocardiography
Electrocardiography
Global Health
Humans
Kounis Syndrome* / diagnosis
Kounis Syndrome* / epidemiology
Kounis Syndrome* / therapy
Morbidity / trends
Myocardial Infarction / epidemiology
Myocardial Infarction / etiology*
Myocardial Revascularization / methods*
Survival Rate / trends

Substances

Anti-Allergic Agents