Impact of the New Kidney Allocation System on Perioperative Outcomes and Costs in Kidney Transplantation

J Am Coll Surg. 2017 Apr;224(4):585-592. doi: 10.1016/j.jamcollsurg.2016.12.009. Epub 2017 Jan 31.

Abstract

Background: In December 2014, a new kidney allocation system (KAS) was implemented nationwide with the goal of improving longevity matching, increasing access to sensitized patients, and improving racial/ethnic disparities.

Study design: National cohort study of US kidney transplantation programs, analyzing hospital-level outcomes (October 2012 to June 2016) using University HealthSystem Consortium data. In-hospital outcomes and costs were analyzed for trends over time using interrupted time series analysis with segmented regression.

Results: There were 38,016 kidney transplantation procedures analyzed during the 3.8-year period. Over time, there was a mean increase of 2.7 cases/month (95% CI -0.02 to 5.4; p = 0.059), unaffected by KAS (18.9 case increase; p = 0.5601). Implementation of KAS led to significant changes in patient demographics, including a decrease in age (-2.8 years; p < 0.001), increase in number of African Americans (3.8%; p < 0.001), decrease in number of Caucasians (6.0%; p < 0.001), increase in number of Hispanics (2.9%; p < 0.001), increase in congestive heart failure (1.3%; p < 0.001), and decrease in diabetes with complications (4.0%; p < 0.001). The KAS had no impact on length of stay (0.12 days; 95% CI -0.11 to 0.35), length of stay index (0.01; 95% CI -0.03 to 0.05), ICU cases, ICU length of stay, patient safety indicators, or in-hospital mortality. The KAS led to a significant increase in delayed graft function rates (5.4%; 95% CI 23.3% to 7.4%); total in-hospital costs ($2,429; 95% CI $594 to $4.263); and 7-day (2.2%), 14-day (2.6%), and 30-day (2.7%) readmission rates.

Conclusions: Policy changes in organ allocation can have a significant impact on perioperative costs and outcomes, which can have a downstream influence on transplantation center perisurgical care processes.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Female
  • Health Care Rationing / methods*
  • Health Care Rationing / organization & administration
  • Health Policy / economics*
  • Healthcare Disparities / ethnology
  • Healthcare Disparities / statistics & numerical data
  • Healthcare Disparities / trends*
  • Hospital Costs / statistics & numerical data
  • Hospital Costs / trends*
  • Humans
  • Kidney Transplantation / economics*
  • Kidney Transplantation / standards
  • Kidney Transplantation / statistics & numerical data
  • Kidney Transplantation / trends
  • Length of Stay / economics
  • Length of Stay / statistics & numerical data
  • Male
  • Middle Aged
  • Outcome and Process Assessment, Health Care
  • Patient Readmission / economics
  • Patient Readmission / statistics & numerical data
  • Postoperative Complications / economics
  • Postoperative Complications / epidemiology
  • United States
  • Young Adult