[Genital warts in HIV-infected individuals]

Hautarzt. 2017 Mar;68(3):192-198. doi: 10.1007/s00105-017-3938-z.
[Article in German]


Anogenital warts (condylomata acuminata) are much more frequent in human immunodeficiency (HIV)-positive patients compared to HIV-negative individuals. Anogenital warts of HIV-infected patients differ from those of HIV-negative individuals with respect to their spread, occurrence on more unusual anatomical sites, human papillomavirus (HPV)-type spectrum, tendency to recur, and risk of malignant transformation. Between 18 and 56% of anogenital warts of HIV-positive patients harbor high-grade dysplasia. Therefore, anogenital warts of HIV-infected patients should be preferentially treated with ablative methods and should be evaluated histopathologically. Gender-neutral prophylactic HPV vaccination of HPV-naive boys and girls could also lead to a significant reduction of anogenital warts in this patient group in the future.

Keywords: Anogenital warts; Condylomata acuminata; Genital warts; Human papillomavirus; Vaccination.

Publication types

  • Review

MeSH terms

  • Condylomata Acuminata / diagnosis*
  • Condylomata Acuminata / therapy*
  • Condylomata Acuminata / virology
  • Diagnosis, Differential
  • Evidence-Based Medicine
  • HIV Infections / diagnosis*
  • HIV Infections / therapy*
  • HIV Infections / virology
  • Humans
  • Papillomavirus Infections / diagnosis
  • Papillomavirus Infections / prevention & control
  • Papillomavirus Infections / virology*
  • Precancerous Conditions / diagnosis
  • Precancerous Conditions / prevention & control
  • Precancerous Conditions / virology*
  • Treatment Outcome