[Endobronchial tuberculosis]

Rev Pneumol Clin. 2017 Apr;73(2):55-60. doi: 10.1016/j.pneumo.2016.12.003. Epub 2017 Feb 2.
[Article in French]

Abstract

Background/aim: The endobronchial tuberculosis (EBTB) is an uncommon type of tuberculosis. The respiratory symptoms in EBTB are usually nonspecific and misleading. The aim of the study is to determine the clinical features and diagnostic aspects of EBTB.

Patients and methods: Twenty-eight cases of endobronchial tuberculosis collected from January 2009 to October 2015.

Results: EBTB was found in 16 females and 12 males. The mean age was 48 years. The history of tuberculosis and tuberculosis contagion were not found in any case. The respiratory symptoms were dominated by cough and dyspnea. Hemoptysis was found in 7 cases. The chest X-ray showed associated pulmonary lesions in 26 cases. Bronchoscopy finded an endobronchial granular lesion in 15 cases, a tumorous pattern in 7 cases; a thickening spurs in 4 cases and ganglio-bronchial fistula in two cases. Bronchial biopsies had found a caseo-follicular tuberculosis in 27 cases. Pleural biopsy confirmed associated pleural tuberculosis in one case. The research of Koch bacillus in the sputum was positive in 13 cases and culture in 6 cases. The antituberculosis treatment was started in all patients and an oral corticosteroids treatment was associated in 5 cases. The evolution was good in 26 cases.

Conclusion: This study showed clinical, radiological and endoscopic bronchial tuberculosis polymorphism making its diagnosis difficult and the importance of a bacteriological and/or histological confirmation.

Keywords: Antituberculosis treatment; Bacille de Koch; Bronchoscopie; Bronchoscopy; Endobronchial tuberculosis; Histologie; Histology; Koch bacillus; Polymorphism; Polymorphisme; Traitement anti-bacillaire; Tuberculose endobronchique.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antitubercular Agents / therapeutic use
  • Bronchial Diseases* / diagnosis
  • Bronchial Diseases* / drug therapy
  • Bronchial Diseases* / epidemiology
  • Bronchoscopy
  • Diabetes Complications / diagnosis
  • Diabetes Complications / drug therapy
  • Diabetes Complications / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Morocco / epidemiology
  • Retrospective Studies
  • Smoking / epidemiology
  • Socioeconomic Factors
  • Tuberculosis, Pulmonary* / diagnosis
  • Tuberculosis, Pulmonary* / drug therapy
  • Tuberculosis, Pulmonary* / epidemiology
  • Young Adult

Substances

  • Antitubercular Agents