Diet and the Microbiome

Gastroenterol Clin North Am. 2017 Mar;46(1):49-60. doi: 10.1016/j.gtc.2016.09.005. Epub 2017 Jan 4.

Abstract

The gut microbiota provides a range of ecologic, metabolic, and immunomodulatory functions relevant to health and well-being. The gut microbiota not only responds quickly to changes in diet, but this dynamic equilibrium may be managed to prevent and/or treat acute and chronic diseases. This article provides a working definition of the term "microbiome" and uses two examples of dietary interventions for the treatment of large bowel conditions to emphasize the links between diet and microbiome. There remains a need to develop a better functional understanding of the microbiota, if its management for clinical utility is to be fully realized.

Keywords: Diet; Gut; Inflammatory bowel disease; Irritable bowel syndrome; Microbiome; Microbiota.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Diet*
  • Gastrointestinal Microbiome*
  • Humans
  • Inflammatory Bowel Diseases / diet therapy
  • Inflammatory Bowel Diseases / microbiology*
  • Irritable Bowel Syndrome / diet therapy
  • Irritable Bowel Syndrome / microbiology*