Metaphase Spindle Assembly

Biology (Basel). 2017 Feb 3;6(1):8. doi: 10.3390/biology6010008.


A microtubule-based bipolar spindle is required for error-free chromosome segregation during cell division. In this review I discuss the molecular mechanisms required for the assembly of this dynamic micrometer-scale structure in animal cells.

Keywords: cell division; chromosome; dynein; kinesin; metaphase; microtubules; mitosis.

Publication types

  • Review