Pediatric Exposures to Veterinary Pharmaceuticals

Pediatrics. 2017 Mar;139(3):e20161496. doi: 10.1542/peds.2016-1496. Epub 2017 Feb 6.

Abstract

Objective: To describe the epidemiology of veterinary pharmaceutical-related exposures to children based on calls to a regional poison control center.

Methods: A retrospective analysis of pediatric (≤19 years of age) exposures to pharmaceutical products intended for animal use, managed by a regional poison control center from 1999 through 2013, was conducted. Case narratives were reviewed and coded for exposure-related circumstances and intended species. Descriptive statistics were generated.

Results: From 1999 through 2013, the Central Ohio Poison Center received 1431 calls that related to a veterinary pharmaceutical exposure for children ≤19 years of age. Most of the pediatric calls (87.6%) involved children ≤5 years of age. Exploratory behavior was the most common exposure-related circumstance (61.4%) and ingestion accounted for the exposure route in 93% of cases. Substances commonly associated with exposures included: veterinary drugs without human equivalent (17.3%), antimicrobial agents (14.8%), and antiparasitics (14.6%). Based on substance and quantity, the majority of exposures (96.9%) were not expected to result in long-term or lasting health effects and were managed at home (94.1%). A total of 80 cases (5.6%) were referred to a health care facility, and 2 cases resulted in a moderate health effect.

Conclusions: Children ≤5 years of age are most at risk for veterinary pharmaceutical-related exposures. Although most exposures do not result in a serious medical outcome, efforts to increase public awareness, appropriate product dispensing procedures, and attention to home storage practices may reduce the risk of veterinary pharmaceutical exposures to young children.

MeSH terms

  • Accidents, Home / statistics & numerical data*
  • Adolescent
  • Age Distribution
  • Analgesics / poisoning
  • Animals
  • Anti-Infective Agents / poisoning
  • Antiparasitic Agents / poisoning
  • Child
  • Child, Preschool
  • Exploratory Behavior
  • Female
  • Humans
  • Male
  • Ohio / epidemiology
  • Poison Control Centers*
  • Retrospective Studies
  • Veterinary Drugs / poisoning*
  • Young Adult

Substances

  • Analgesics
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Veterinary Drugs