Assessing the Impact of Perinatal HIV Case Management on Outcomes Along the HIV Care Continuum for Pregnant and Postpartum Women Living With HIV, Philadelphia 2005-2013

AIDS Behav. 2017 Sep;21(9):2670-2681. doi: 10.1007/s10461-017-1714-9.


To evaluate the impact of a Perinatal Medical Case Management (PCM) Program for women living with HIV (WLWH). Characteristics of pregnant and postpartum WLWH were compared between those who engaged in PCM and those who did not. Using secondary data collected from routine HIV surveillance, multivariable regression models were used to evaluate the association between PCM and four outcomes adapted from the HIV care continuum. In multivariable models, compared to WLWH not in PCM, participants (n = 448, 52.8%) were almost twice as likely to achieve HIV suppression before delivery (aOR 1.90 [1.33, 2.71], p = 0.0005); were more likely to be retained in HIV care 1 year postpartum (aOR 1.59 [1.17, 2.16], p = 0.0029); and were equally likely to engage in HIV care within 90-days of delivery (aOR 1.21 [0.88, 1.65], p = 0.236) and be virally suppressed 1 year postpartum (aOR 1.26 [0.90, 1.77], p = 0.178). PCM is an important intervention for preventing perinatal HIV transmission and closings gaps in the HIV care continuum for WLWH during pregnancy and postpartum.

Keywords: HIV care continuum; HIV perinatal medical case management intervention; PMTCT; Prevention perinatal HIV transmission.

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Anti-HIV Agents / therapeutic use*
  • Case Management
  • Continuity of Patient Care*
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / prevention & control
  • HIV Infections / virology
  • Humans
  • Infectious Disease Transmission, Vertical / prevention & control*
  • Mothers
  • Multivariate Analysis
  • Philadelphia / epidemiology
  • Population Surveillance
  • Postpartum Period*
  • Pregnancy
  • Pregnancy Complications, Infectious / prevention & control*
  • Pregnancy Outcome
  • Pregnant Women
  • Treatment Outcome
  • Viral Load


  • Anti-HIV Agents