Plasmid-mediated Tet M in Haemophilus ducreyi

Antimicrob Agents Chemother. 1989 Sep;33(9):1611-3. doi: 10.1128/AAC.33.9.1611.

Abstract

A tetracycline-resistant Haemophilus ducreyi strain isolated in the United States was shown to carry a 34-megadalton plasmid which hybridized with the 1.8-kilobase KpnI-HindIII Tet M probe. The complete Tn916 transposon hybridized with five different bands from this plasmid, suggesting homology throughout the length of the transposon.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Ampicillin / pharmacology
  • Blotting, Southern
  • DNA, Bacterial / biosynthesis
  • Genes, Bacterial*
  • Haemophilus ducreyi / genetics*
  • Molecular Weight
  • Nucleic Acid Hybridization
  • Penicillin Resistance
  • Plasmids*
  • Tetracycline Resistance*
  • Transfection

Substances

  • DNA, Bacterial
  • Ampicillin