Cerebrospinal Fluid and Hydrocephalus: Physiology, Diagnosis, and Treatment

Cancer Control. 2017 Jan;24(1):6-8. doi: 10.1177/107327481702400102.


Background: Cerebrospinal fluid (CSF) is found around and inside the brain and vertebral column. CSF plays a crucial role in the protection and homeostasis of neural tissue.

Methods: Key points on the physiology of CSF as well as the diagnostic and treatment options for hydrocephalus are discussed.

Results: Understanding the fundamentals of the production, absorption, dynamics, and pathophysiology of CSF is crucial for addressing hydrocephalus. Shunts and endoscopic third ventriculostomy have changed the therapeutic landscape of hydrocephalus.

Conclusions: The treatment of hydrocephalus in adults and children represents a large part of everyday practice for the neurologist, both in benign cases and cancer-related diagnoses.

MeSH terms

  • Adult
  • Cerebrospinal Fluid / chemistry*
  • Cerebrospinal Fluid / physiology*
  • Humans
  • Hydrocephalus / cerebrospinal fluid
  • Hydrocephalus / diagnosis*
  • Hydrocephalus / surgery*