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Review
. 2017 Feb 9;12(2):e0170212.
doi: 10.1371/journal.pone.0170212. eCollection 2017.

Tai chi for health benefits in patients with multiple sclerosis: A systematic review

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Free PMC article
Review

Tai chi for health benefits in patients with multiple sclerosis: A systematic review

Liye Zou et al. PLoS One. .
Free PMC article

Abstract

The aim of this systematic review was to evaluate the existing evidence on the effectiveness and safety of Tai chi, which is critical to provide guidelines for clinicians to improve symptomatic management in patients with multiple sclerosis (MS). After performing electronic and manual searches of many sources, ten relevant peer-reviewed studies that met the inclusion criteria were retrieved. The existing evidence supports the effectiveness of Tai chi on improving quality of life (QOL) and functional balance in MS patients. A small number of these studies also reported the positive effect of Tai chi on flexibility, leg strength, gait, and pain. The effect of Tai chi on fatigue is inconsistent across studies. Although the findings demonstrate beneficial effects on improving outcome measures, especially for functional balance and QOL improvements, a conclusive claim should be made carefully for reasons such as methodological flaws, small sample size, lack of specific-disease instruments, unclear description of Tai chi protocol, unreported safety of Tai chi, and insufficient follow-up as documented by the existing literature. Future research should recruit a larger number of participants and utilize the experimental design with a long-term follow-up to ascertain the benefits of Tai chi for MS patients.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Flow chart showing the study selection.

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References

    1. Franklin RJM, Edgar JM, Smith KJ. Neuroprotection and repair in multiple sclerosis. Nat Rev Neurol 2012; 8:624–34. 10.1038/nrneurol.2012.200 - DOI - PubMed
    1. Chiaravalloti ND, DeLuca J. Cognitive impairment in multiple sclerosis. Lancet Neurol 2008; 7:1139–51. 10.1016/S1474-4422(08)70259-X - DOI - PubMed
    1. Amato MP, Ponziani G, Rossi F, Liedl CL, Stefaine C, Rossi L. Quality of life in multiple sclerosis: the impact of depression, fatigue and disability. Mult Scler 2001; 7: 340–4. - PubMed
    1. Benedict RHB, Wahlig E, Bakshi R, Fishman I, Munschauer F, Zivadinov, et al. Predicting quality of life in multiple sclerosis: accounting for physical disability, fatigue, cognition, mood disorder, personality, and behavior change. J Neurol Sci 2005; 231:29–34. 10.1016/j.jns.2004.12.009 - DOI - PubMed
    1. Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol Sci 2001; 22: 117–39. - PubMed

Grants and funding

The author(s) received no specific funding for this work.