Dentate Mossy Cell and Pattern Separation

Neuron. 2017 Feb 8;93(3):465-467. doi: 10.1016/j.neuron.2017.01.021.


Three studies by Danielson et al. (2017), GoodSmith et al. (2017), and Sensai and Buzsáki (2017) distinguish in vivo firing properties of dentate mossy cells from granule cells during behavior. Robust spatial remapping of mossy cells, in contrast to sparse firing of granule cells, suggests differential involvement in pattern separation.

MeSH terms

  • Dentate Gyrus / cytology*
  • Mossy Fibers, Hippocampal*
  • Neurons / cytology