Techniques and outcomes of microsurgical management of ruptured and unruptured fusiform cerebral aneurysms

J Neurosurg. 2017 Dec;127(6):1353-1360. doi: 10.3171/2016.9.JNS161165. Epub 2017 Feb 10.


OBJECTIVE Fusiform cerebral aneurysms represent a small portion of intracranial aneurysms; differ in natural history, anatomy, and pathology; and can be difficult to treat compared with saccular aneurysms. The purpose of this study was to examine the techniques of treatment of ruptured and unruptured fusiform intracranial aneurysms and patient outcomes. METHODS In 45 patients with fusiform aneurysms, the authors retrospectively reviewed the presentation, location, and shape of the aneurysm; the microsurgical technique; the outcome at discharge and last follow-up; and the change in the aneurysm at last angiographic follow-up. RESULTS Overall, 48 fusiform aneurysms were treated in 45 patients (18 male, 27 female) with a mean age of 49 years (median 51 years; range 6 months-76 years). Twelve patients (27%) had ruptured aneurysms and 33 (73%) had unruptured aneurysms. The mean aneurysm size was 8.9 mm (range 6-28 mm). The aneurysms were treated by clip reconstruction (n = 22 [46%]), clip-wrapping (n = 18 [38%]), and vascular bypass (n = 8 [17%]). The mean (SD) hospital stay was 19.0 ± 7.4 days for the 12 patients with subarachnoid hemorrhage and 7.0 ± 5.6 days for the 33 patients with unruptured aneurysms. The mean follow-up was 38.7 ± 29.5 months (median 36 months; range 6-96 months). The mean Glasgow Outcome Scale score for the 12 patients with subarachnoid hemorrhage was 3.9; for the 33 patients with unruptured aneurysms, it was 4.8. No rehemorrhages occurred during follow-up. The overall annual risk of recurrence was 2% and that of rehemorrhage was 0%. CONCLUSIONS Fusiform and dolichoectatic aneurysms involving the entire vessel wall must be investigated individually. Although some of these aneurysms may be amenable to primary clipping and clip reconstruction, these complex lesions often require alternative microsurgical and endovascular treatment. These techniques can be performed with acceptable morbidity and mortality rates and with low rates of early rebleeding and recurrence.

Keywords: ACA = anterior cerebral artery; CTA = CT angiography; Gore-Tex clipping technique; MCA = middle cerebral artery; PED = Pipeline Embolization Device; PICA = posterior inferior cerebellar artery; cerebral aneurysm; microsurgery; microsurgical clipping; ruptured aneurysm; subarachnoid hemorrhage; unruptured aneurysm; vascular disorders.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aneurysm, Ruptured / surgery*
  • Child
  • Child, Preschool
  • Endovascular Procedures / methods*
  • Female
  • Humans
  • Infant
  • Intracranial Aneurysm / surgery*
  • Male
  • Microsurgery / methods*
  • Middle Aged
  • Neurosurgical Procedures / methods*
  • Surgical Instruments
  • Treatment Outcome
  • Young Adult