Brief Report: Longitudinal Opioid Use Among HIV-Infected Patients, 2000 to 2014

J Acquir Immune Defic Syndr. 2017 May 1;75(1):77-80. doi: 10.1097/QAI.0000000000001321.


Longitudinal opioid prescription use is unknown among HIV-infected patients. Group-based trajectory modeling followed by multinomial logistic regression was used to identify distinct trajectories and their association with baseline characteristics among 1239 HIV-infected UNC CFAR HIV Clinical Cohort participants, 2000-2014. Three trajectories were identified: (1) 72% never/sporadic opioid use (referent group), (2) 11% episodic use (associated with female sex, depression, drug-related diagnoses, antiretroviral therapy use, and undetectable HIV RNA), and (3) 16% chronic use (associated with older age, female sex, and mental health diagnoses). Overall, opioid prescription decreased substantially with longer time in HIV care among both episodic and chronic users.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage*
  • Female
  • HIV Infections / complications*
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Substance-Related Disorders / epidemiology*
  • Young Adult


  • Analgesics, Opioid