Examiner's finger-mounted near-infrared spectroscopy is feasible to analyze cerebral and skeletal muscle oxygenation in conscious Chihuahuas

J Biomed Opt. 2017 Feb 1;22(2):26006. doi: 10.1117/1.JBO.22.2.026006.

Abstract

To measure regional saturation of oxygen ( rSO 2 ) of hemoglobin and total hemoglobin index (HbI) in the brain (through the molera of the head) and skeletal muscle (musculus gracilis) of conscious Chihuahua dogs using an examiner’s finger-mounted near-infrared spectroscopy (NIRS) device, Toccare, we investigated brain and skeletal muscle NIRS in 48 Chihuahuas without severe disease. To measure rSO 2 and total HbI, a Toccare probe was placed on the molera of the head and musculus gracilis of each dog for real-time recording. Stable NIRS values were obtained within 10 s. We also examined the effect of anesthesia on rSO 2 and total HbI of a Chihuahua. Cerebral rSO 2 values ( 59 % ± 7 % ) were significantly lower than those obtained at femoral regions ( 67 % ± 6 % ), whereas total HbI values in the brain ( 0.38 ± 0.09 ) were significantly higher than those of the musculus gracilis ( 0.20 ± 0.05 ). Sedation with a combination of medetomidine and ketamine decreased cerebral rSO 2 along with a corresponding reduction in heart rate. Sevoflurane anesthesia with 100% O 2 maintained rSO 2 in the brain with a

MeSH terms

  • Anesthetics / pharmacology
  • Animals
  • Brain Chemistry* / drug effects
  • Cerebrovascular Circulation / drug effects
  • Dogs
  • Hemoglobins / analysis
  • Muscle, Skeletal / chemistry*
  • Muscle, Skeletal / drug effects
  • Oxygen / analysis
  • Spectroscopy, Near-Infrared / instrumentation*

Substances

  • Anesthetics
  • Hemoglobins
  • Oxygen