Toward precision medicine in myotonic syndromes

Oncotarget. 2017 Feb 28;8(9):14279-14280. doi: 10.18632/oncotarget.15263.
No abstract available

Keywords: Neuroscience; mexiletine; myotonia; precision medicine; rare disease; sodium channels.

Publication types

  • Editorial

MeSH terms

  • Amines
  • Animals
  • Anti-Arrhythmia Agents / pharmacology
  • Chloride Channels / metabolism
  • Humans
  • Ligands
  • Mexiletine / pharmacology
  • Mice
  • Muscle, Skeletal / pathology
  • Muscular Diseases / drug therapy
  • Muscular Diseases / metabolism*
  • Muscular Diseases / physiopathology
  • Mutation
  • Precision Medicine / methods*
  • Rats
  • Sarcolemma / pathology
  • Sodium Channel Blockers / pharmacology
  • Syndrome

Substances

  • Amines
  • Anti-Arrhythmia Agents
  • Chloride Channels
  • Ligands
  • Sodium Channel Blockers
  • Mexiletine