LASER server: ancestry tracing with genotypes or sequence reads

Bioinformatics. 2017 Jul 1;33(13):2056-2058. doi: 10.1093/bioinformatics/btx075.


Summary: To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user-friendly interactive visualization of the results.

Availability and implementation: The LASER server is freely accessible at

Contact: or

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Genetic Variation*
  • Humans
  • Phylogeography / methods*
  • Population Groups / genetics*
  • Sequence Analysis, DNA / methods*
  • Software*