Deterrent activity of hops flavonoids and their derivatives against stored product pests

Bull Entomol Res. 2017 Oct;107(5):592-597. doi: 10.1017/S0007485317000050. Epub 2017 Feb 16.

Abstract

Five flavonoids from hops, two of their derivatives, along with naringenin used as a model compound, were tested for their antifeedant activity against three coleopteran stored product pests: Sitophilus granarius L., Tribolium confusum Duv. and Trogoderma granarium Everts. The introduction, into the tested flavonoid molecules, of additional structural fragments such as prenyl or dimethylpyran moiety, is proposed to significantly alter the deterrent activity of the compounds. The prenyl moiety in flavonoids increased the deterrent activity of these compounds in all three of the grain feeding species used in the tests. It is also concluded that the introduction of dimethylpyran moiety to the flavonoid structure increases its deterrent activity in S. granarius and T. confusum, but in one of the test insects, T. granarium, an increased feeding was observed in response to the introduction of dimethylpyran moiety to the flavonoid structure.

Keywords: antifeedant activity; hop flavonoids; hop flavonoids derivatives; stored product pests.

Publication types

  • Evaluation Study

MeSH terms

  • Animals
  • Feeding Behavior / drug effects*
  • Flavonoids / pharmacology*
  • Food Parasitology
  • Humulus / chemistry*
  • Insect Repellents / analysis*
  • Insect Repellents / pharmacology
  • Larva / drug effects
  • Tribolium / drug effects*
  • Weevils / drug effects*

Substances

  • Flavonoids
  • Insect Repellents