Relationship Between Central Obesity and Spread of Spinal Anesthesia in Female Patients

Anesth Analg. 2017 May;124(5):1670-1673. doi: 10.1213/ANE.0000000000001817.


Central obesity may be related to the spread of spinal anesthesia in female patients. Fifty-seven female patients undergoing spinal anesthesia were allocated to either the central obesity or noncentral obesity group. After induction of spinal anesthesia, maximal sensory blockade (primary outcome), time for maximal sensory block, maximum motor block, time to maximum motor block, time to L2 regression, and time to Bromage scale 0 were evaluated. Multiple linear regression analyses showed that maximal sensory blockade was related to central obesity (P = .004). Central obesity is related to a more extensive spread of spinal anesthesia in female patients.

MeSH terms

  • Aged
  • Anesthesia, Spinal / methods*
  • Anesthetics / pharmacokinetics*
  • Anesthetics, Local
  • Bupivacaine
  • Female
  • Humans
  • Hypotension / chemically induced
  • Hypotension / epidemiology
  • Middle Aged
  • Nerve Block
  • Obesity, Abdominal / cerebrospinal fluid
  • Obesity, Abdominal / physiopathology*
  • Treatment Outcome


  • Anesthetics
  • Anesthetics, Local
  • Bupivacaine

Associated data

  • CRiS/KCT0001664