Percutaneous Transcatheter Therapies for the Management of Left Ventricular Assist Device Complications

J Invasive Cardiol. 2017 May;29(5):151-162. Epub 2017 Feb 15.


Heart failure is a growing epidemic in the United States and throughout the world. The utilization of continuous-flow left ventricular assist devices (LVADs) has greatly increased over the last decade. In addition, a limited supply of organ donors has led to a rise in the use, and duration, of LVADs for destination therapy. The increased use of LVAD therapy has led to the observation of mechanical complications such as device thrombosis, de novo aortic insufficiency, and outflow graft stenosis, all of which are associated with prolonged LVAD support. Surgical repair for these complications remains the therapy of choice; however, surgery may be associated with high operative risk in some patients. The purpose of this article is to discuss mechanical complications associated with LVAD therapy and interventional transcatheter therapies that have been used to solve these increasingly complex problems.

Publication types

  • Review

MeSH terms

  • Aortic Valve Insufficiency / diagnostic imaging
  • Aortic Valve Insufficiency / etiology
  • Aortic Valve Insufficiency / therapy*
  • Cardiac Catheterization / methods
  • Endovascular Procedures / methods*
  • Female
  • Heart Failure / diagnosis
  • Heart Failure / surgery*
  • Heart-Assist Devices / adverse effects*
  • Humans
  • Male
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / therapy
  • Prognosis
  • Prosthesis Failure*
  • Risk Assessment
  • Treatment Outcome
  • United States