Abstract
Vascularized composite tissue allografts include skin, which frequently undergoes, in the early post-graft period, acute rejections. The diagnosis of acute rejection may be difficult as it can be mimicked by several dermatoses. We present a bilateral hand allograft recipient who developed, 16.5 years post-graft, cutaneous lesions raising suspicion about rejection. Physical examination and skin biopsy were diagnostic of scabies. This ectoparasitosis should be added in the list of dermatoses that can mimic allograft rejection in vascular composite allografts.
Keywords:
Sarcoptes scabiei; acute rejection; hand allografts; scabies; skin; vascularized composite allografts.
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
MeSH terms
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Allografts / parasitology
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Allografts / pathology
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Animals
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Antiparasitic Agents / therapeutic use
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Biopsy
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Diagnosis, Differential
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Graft Rejection / diagnosis*
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Graft Rejection / pathology
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Graft Rejection / prevention & control
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Hand Transplantation / adverse effects*
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Humans
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Immunosuppression Therapy / adverse effects*
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Immunosuppression Therapy / methods
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Immunosuppressive Agents / therapeutic use*
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Ivermectin / therapeutic use
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Male
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Microscopy
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Middle Aged
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Sarcoptes scabiei
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Scabies / diagnosis*
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Scabies / drug therapy
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Scabies / parasitology
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Scabies / pathology
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Skin / parasitology
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Skin / pathology
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Transplantation, Homologous / adverse effects
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Vascularized Composite Allotransplantation / adverse effects*
Substances
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Antiparasitic Agents
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Immunosuppressive Agents
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Ivermectin