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Review
, 128, 24-32

ProBiS Tools (Algorithm, Database, and Web Servers) for Predicting and Modeling of Biologically Interesting Proteins

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Review

ProBiS Tools (Algorithm, Database, and Web Servers) for Predicting and Modeling of Biologically Interesting Proteins

Janez Konc et al. Prog Biophys Mol Biol.

Abstract

ProBiS (Protein Binding Sites) Tools consist of algorithm, database, and web servers for prediction of binding sites and protein ligands based on the detection of structurally similar binding sites in the Protein Data Bank. In this article, we review the operations that ProBiS Tools perform, provide comments on the evolution of the tools, and give some implementation details. We review some of its applications to biologically interesting proteins. ProBiS Tools are freely available at http://probis.cmm.ki.si and http://probis.nih.gov.

Keywords: Binding sites; Prediction; ProBiS; Protein structure; Structural similarity.

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