Barriers Associated With Door-to-Balloon Delay in Contemporary Japanese Practice

Circ J. 2017 May 25;81(6):815-822. doi: 10.1253/circj.CJ-16-0905. Epub 2017 Feb 23.

Abstract

Background: Door-to-balloon (DTB) time ≤90 min is an important quality indicator in the management of ST-elevation myocardial infarction (STEMI), but a considerable number of patients still do not meet this goal, particularly in countries outside the USA and Europe.Methods and Results:We analyzed 2,428 STEMI patients who underwent primary PCI ≤12 h of symptom onset who were registered in an ongoing prospective multicenter database (JCD-KiCS registry), between 2008 and 2013. We analyzed both the time trend in DTB time within this cohort in the registry, and independent predictors of delayed DTB time >90 min. Median DTB time was 90 min (IQR, 68-115 min) during the study period and there were no significant changes with year. Predictors for delay in DTB time included peripheral artery disease, prior revascularization, off-hour arrival, age >75 years, heart failure at arrival, and use of IABP or VA-ECMO. Notably, high-volume PCI-capable institutions (PCI ≥200/year) were more adept at achieving shorter DTB time compared with low-volume institutions (PCI <200/year).

Conclusions: Half of the present STEMI patients did not achieve DTB time ≤90 min. Targeting the elderly and patients with multiple comorbidities, and PCI performed in off-hours may aid in its improvement.

Keywords: Acute coronary syndrome; Door-to-balloon time; Reperfusion; ST-segment elevation myocardial infarction.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Aged
  • Female
  • Hospitalization*
  • Humans
  • Japan
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention*
  • Registries*
  • ST Elevation Myocardial Infarction*
  • Time Factors