One-Pot Conversion of Epoxidized Soybean Oil (ESO) into Soy-Based Polyurethanes by MoCl₂O₂ Catalysis

Molecules. 2017 Feb 21;22(2):333. doi: 10.3390/molecules22020333.


An innovative and eco-friendly one-pot synthesis of bio-based polyurethanes is proposed via the epoxy-ring opening of epoxidized soybean oil (ESO) with methanol, followed by the reaction of methoxy bio-polyols intermediates with 2,6-tolyl-diisocyanate (TDI). Both synthetic steps, methanolysis and polyurethane linkage formation, are promoted by a unique catalyst, molybdenum(VI) dichloride dioxide (MoCl₂O₂), which makes this procedure an efficient, cost-effective, and environmentally safer method amenable to industrial scale-up.

Keywords: bio-based polyurethane; catalysis; one-pot synthesis; oxidation.

MeSH terms

  • Catalysis
  • Chemistry Techniques, Synthetic*
  • Oxidation-Reduction
  • Polyurethanes / chemical synthesis*
  • Proton Magnetic Resonance Spectroscopy
  • Soybean Oil / chemistry*


  • Polyurethanes
  • epoxidized soybean oil
  • Soybean Oil