Diagnostic and therapeutic modalities for 287 malignant and benign salivary tumors: A cohort study

J Craniomaxillofac Surg. 2017 Apr;45(4):585-588. doi: 10.1016/j.jcms.2017.01.017. Epub 2017 Jan 25.

Abstract

Background: Salivary gland tumors (SGT's), 3-10% of head/neck tumors, exhibit a striking range of morphological diversity. This minimally symptomatic disease can be challenging to diagnose, and therapeutic policy is still controversial.

Methods: We compared benign and malignant cohorts according to diagnostic modality utilized and therapeutic modality administered over 20 years in a single medical center.

Results: Of 287 cases, 216 had benign tumors and 71 had malignant tumors. Treatment was surgery-based in 99% of cases, often accompanied by radiotherapy and/or chemotherapy. Rates of imaging and biopsy for diagnosis were significantly higher in malignant than benign tumors. Fine-needle aspiration (FNA) was used in 90.3% of benign tumors. Of 71 malignant tumors, 69 underwent surgery to fully remove the malignant tumor. Adjuvant therapy included 22 neck dissections (30%), 28 radiotherapy (39.4%), 12 chemotherapy (16.9%) and 10 combined radio-chemotherapy (14.1%). Partial parotidectomy, submandibular sialoadenectomy and local excision were used in 78.1%, 8.3% and 6.9% of benign cases. Total parotidectomy, sub-total maxillectomy and wide excision were used in 16.9%, 12.7% and 22.6% of malignant cases.

Discussion: Diagnostic and therapeutic modalities for treatment of salivary tumor at our hospital are presented and discussed with respect to others. A paradigm of therapy administered in our institute is presented.

Keywords: Benign; Diagnosis; Etiology; Malignant; Salivary glands; Tumors.

Publication types

  • Comparative Study

MeSH terms

  • Cohort Studies
  • Humans
  • Retrospective Studies
  • Salivary Gland Neoplasms / classification
  • Salivary Gland Neoplasms / diagnosis*
  • Salivary Gland Neoplasms / therapy*