The first case report of emphysematous pyelonephritis and bacteremia due to Oligella urethralis

Int J Med Microbiol. 2017 Apr;307(3):151-153. doi: 10.1016/j.ijmm.2017.01.004. Epub 2017 Feb 20.

Abstract

Oligella urethralis (O. urethralis) is an organism that rarely causes infections in humans. We report the case of a 90-year-old bedridden woman with progressive dementia who was placed in a long-term-care facility. She was admitted to our hospital due to fever and unconsciousness with pyuria. The abdominal computed tomography showed left pneumatosis and urinary stone. Fluoroquinolones-resistant O. urethralis, which was identified by the Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and the 16S rRNA gene sequencing, was isolated form the blood and urine cultures at admission. To the best of our knowledge, this is the first case of emphysematous pyelonephritis caused by O. urethralis.

Keywords: 16S rRNA gene sequencing; Emphysematous pyelonephritis; Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS); Oligella urethralis (O. urethralis); Rare causative organism; Rare species.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Alcaligenaceae / classification
  • Alcaligenaceae / drug effects
  • Alcaligenaceae / genetics
  • Alcaligenaceae / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Bacteremia / complications*
  • Bacteremia / diagnosis*
  • Bacteremia / microbiology
  • Blood / microbiology
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Drug Resistance, Bacterial
  • Female
  • Fluoroquinolones / pharmacology
  • Gram-Negative Bacterial Infections / diagnosis*
  • Gram-Negative Bacterial Infections / microbiology
  • Humans
  • Long-Term Care
  • Pyelonephritis / complications*
  • Pyelonephritis / diagnosis*
  • Pyelonephritis / microbiology
  • RNA, Ribosomal, 16S / genetics
  • Radiography, Abdominal
  • Sequence Analysis, DNA
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
  • Tomography, X-Ray Computed
  • Urine / microbiology

Substances

  • Anti-Bacterial Agents
  • DNA, Bacterial
  • DNA, Ribosomal
  • Fluoroquinolones
  • RNA, Ribosomal, 16S