Polycystic Ovary Syndrome (PCOS), Diagnostic Criteria, and AMH

Asian Pac J Cancer Prev. 2017 Jan 1;18(1):17-21. doi: 10.22034/APJCP.2017.18.1.17.

Abstract

The polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility and a notable proportion of women of reproductive age are affected. It may constitute a risk factor for cancer development. Different factors could result in different manifestations and many of these are related to predispositions. It is essential to establish criteria to achieve an exact diagnosis of PCOS, especially among adolescent patients because of the overlap between features of PCO syndrome and physiological findings in puberty. Day by day the technology of ultrasonography is improving and accuracy is increasing, but remains dependent on the specific equipment available. Some factors are inter-related in determining PCOS prognosis. Serum AMH is synthesized by small antral follicles, which are precisely those seen on ultrasound and could help us to diagnose PCOS but there are many aspects that still require elucidation. In this mini- review we have attempted to identify some of these correlations.

Keywords: Polycystic ovary syndrome; anti-Müllerian hormone; diagnosis; treatment.