Identification of a receptor for the morphogen retinoic acid

Nature. 1987 Dec 17-23;330(6149):624-9. doi: 10.1038/330624a0.

Abstract

Analysis of complementary DNA encoding a novel gene product reveals striking similarity to the steroid and thyroid hormone receptors. Binding and transcription activational studies show it to be a receptor for the vitamin A-related morphogen retinoic acid.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Carrier Proteins / physiology*
  • DNA-Binding Proteins / physiology*
  • Gene Expression Regulation
  • Genes
  • Genes, Regulator
  • Molecular Sequence Data
  • Morphogenesis
  • Multigene Family
  • Receptors, Retinoic Acid
  • Recombinant Proteins
  • Transcription Factors / physiology*

Substances

  • Carrier Proteins
  • DNA-Binding Proteins
  • Receptors, Retinoic Acid
  • Recombinant Proteins
  • Transcription Factors

Associated data

  • GENBANK/X06614