Identification of a receptor for the morphogen retinoic acid

V Giguere; E S Ong; P Segui; R M Evans

doi:10.1038/330624a0

Identification of a receptor for the morphogen retinoic acid

Nature. 1987 Dec;330(6149):624-9. doi: 10.1038/330624a0.

Authors

V Giguere¹, E S Ong, P Segui, R M Evans

Affiliation

¹ Howard Hughes Medical Institute, Gene Expression Laboratory, Salk Institute for Biological Studies, San Diego, California 92037.

PMID: 2825036
DOI: 10.1038/330624a0

Abstract

Analysis of complementary DNA encoding a novel gene product reveals striking similarity to the steroid and thyroid hormone receptors. Binding and transcription activational studies show it to be a receptor for the vitamin A-related morphogen retinoic acid.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Amino Acid Sequence
Base Sequence
Carrier Proteins / physiology*
DNA-Binding Proteins / physiology*
Gene Expression Regulation
Genes
Genes, Regulator
Molecular Sequence Data
Morphogenesis
Multigene Family
Receptors, Retinoic Acid
Recombinant Proteins
Transcription Factors / physiology*

Substances

Carrier Proteins
DNA-Binding Proteins
Receptors, Retinoic Acid
Recombinant Proteins
Transcription Factors

Associated data

GENBANK/X06614