HIV-Associated Gastrointestinal Cancer

Oncol Res Treat. 2017;40(3):115-118. doi: 10.1159/000456714. Epub 2017 Feb 24.


People living nowadays with HIV and AIDS may be treated effectively regarding virus replication and immunology. However, non-AIDS-defining cancer is of growing relevance due to high incidence and unfavorable outcome. The aim of this review is to summarize current knowledge on gastrointestinal (GI) carcinoma. Although literature on GI cancer is rare, an increased incidence of esophageal, gastric, pancreatic, hepatocellular, and colorectal carcinoma has been demonstrated. However, there are only few reports on therapy strategies and outcome, so that, despite increased occurrence of many GI carcinomas, only little is known about individualized treatment options and outcome in HIV-positive patients. More efforts have to be undertaken to close this gap.

Publication types

  • Review

MeSH terms

  • Anti-Retroviral Agents / administration & dosage*
  • Antineoplastic Agents / administration & dosage*
  • Drug Therapy, Combination / methods
  • Drug Therapy, Combination / standards
  • Evidence-Based Medicine
  • Gastrointestinal Neoplasms / diagnosis*
  • Gastrointestinal Neoplasms / drug therapy*
  • Gastrointestinal Neoplasms / etiology
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy*
  • HIV Infections / etiology
  • Humans
  • Medical Oncology / standards
  • Practice Guidelines as Topic
  • Treatment Outcome


  • Anti-Retroviral Agents
  • Antineoplastic Agents