Necrotic intraocular retinoblastoma associated with orbital cellulitis

Surv Ophthalmol. 2018 Jan-Feb;63(1):114-118. doi: 10.1016/j.survophthal.2017.01.010. Epub 2017 Feb 28.

Abstract

Orbital cellulitis associated with retinoblastoma is uncommon and is characterized by noninfectious inflammation of the periorbital structures. The underlying mechanism is thought to be necrosis of the intraocular tumor, leading to intraocular and periorbital inflammation. We report 2 retinoblastoma patients who presented with an orbital cellulitis-like picture and discuss clinical characteristics, histopathologic features, and treatment.

Keywords: intraocular retinoblastoma; necrotic retinoblastoma; orbital cellulitis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Male
  • Necrosis
  • Orbital Cellulitis / pathology*
  • Retinal Neoplasms / pathology*
  • Retinoblastoma / pathology*