Unsaturated Fatty Acids Maintain Cancer Cell Stemness

Abir Mukherjee; Hilary A Kenny; Ernst Lengyel

doi:10.1016/j.stem.2017.02.008

Unsaturated Fatty Acids Maintain Cancer Cell Stemness

Cell Stem Cell. 2017 Mar 2;20(3):291-292. doi: 10.1016/j.stem.2017.02.008.

Authors

Abir Mukherjee¹, Hilary A Kenny¹, Ernst Lengyel²

Affiliations

¹ Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL 60637, USA.
² Department of Obstetrics and Gynecology/Section of Gynecologic Oncology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: elengyel@uchicago.edu.

Abstract

Investigation of the metabolic regulation of cancer stem cells is an emerging field that offers promising approaches for identifying and targeting recalcitrant stem cell populations. In this issue of Cell Stem Cell, Li et al. (2017) indicate that increased lipid desaturation is essential to stem-like characteristics in ovarian cancer cells.

Publication types

Comment

MeSH terms

Fatty Acids, Unsaturated*
Humans
Neoplastic Stem Cells*

Substances

Fatty Acids, Unsaturated

Abstract

Publication types

MeSH terms

Substances

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