Prevention and management of ovarian hyperstimulation syndrome

Thromb Res. 2017 Mar:151 Suppl 1:S61-S64. doi: 10.1016/S0049-3848(17)30070-1.

Abstract

Ovarian hyperstimulation syndrome (OHSS) is a serious iatrogenic complication of ovarian stimulation. It is feasible to identify patients at risk, modify stimulation strategies to ameliorate risk, and initiate out-patient treatments that alter disease pathophysiology to reduce disease severity. Mitigation of OHSS risk and severity, through innovative approaches prior to treatment, during treatment and after treatment should now be standard care. This review summarizes recent developments and provides recommendations on the prevention and treatment of OHSS.

Keywords: IVF; Ovarian hyperstimulation syndrome (OHSS); Prevention; Treatment.

Publication types

  • Review

MeSH terms

  • Aspirin / therapeutic use
  • Calcium Gluconate / therapeutic use
  • Cyclooxygenase Inhibitors / therapeutic use
  • Disease Management
  • Dopamine Agonists / therapeutic use
  • Female
  • Gonadotropin-Releasing Hormone / antagonists & inhibitors
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Metformin / therapeutic use
  • Ovarian Hyperstimulation Syndrome / etiology*
  • Ovarian Hyperstimulation Syndrome / prevention & control
  • Ovarian Hyperstimulation Syndrome / therapy*
  • Ovulation Induction / adverse effects*
  • Ovulation Induction / methods*

Substances

  • Cyclooxygenase Inhibitors
  • Dopamine Agonists
  • Hypoglycemic Agents
  • Gonadotropin-Releasing Hormone
  • Metformin
  • Aspirin
  • Calcium Gluconate