Adenoid cystic-like tumor of the prostate gland. A report of two cases and review of the literature on "adenoid cystic carcinoma" of the prostate

Am J Clin Pathol. 1988 Jan;89(1):49-56. doi: 10.1093/ajcp/89.1.49.


Two prostatic neoplasms that closely resemble adenoid cystic carcinoma of the salivary glands, but in the authors' opinion merit separate designation, are reported. Most of the well-documented examples of prostatic lesions interpreted as "adenoid cystic carcinoma" appear to have been similar to the cases reported herein. The lesions in this report, which the authors have designated as adenoid cystic-like tumors, occurred in men of 60 and 68 years of age who presented with urinary tract obstruction and had transurethral resection of the prostate. Both neoplasms were associated with a minor component of prostatic adenocarcinoma of the usual acinar type. Each adenoid cystic-like tumor had areas that closely resembled basal cell hyperplasia of the prostate, and one had conspicuous foci of squamous differentiation. One patient had a radical prostatectomy and is well six years after operation. The other patient was treated with transurethral resection and irradiation and is well eight months after operation. The prognosis associated with this neoplasm appears to be excellent on the basis of the limited experience to date.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Carcinoma, Adenoid Cystic / pathology
  • Carcinoma, Adenoid Cystic / ultrastructure
  • Humans
  • Male
  • Middle Aged
  • Prostatic Neoplasms / pathology*
  • Prostatic Neoplasms / ultrastructure